The impact of vaccination on the evolution of COVID-19 in Portugal

Autor: Beatriz Machado, Liliana Antunes, Constantino Caetano, João F. Pereira, Baltazar Nunes, Paula Patrício, M. Luísa Morgado
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Mathematical Biosciences and Engineering, Vol 19, Iss 1, Pp 936-952 (2022)
Druh dokumentu: article
ISSN: 1551-0018
DOI: 10.3934/mbe.2022043?viewType=HTML
Popis: In this work we use simple mathematical models to study the impact of vaccination against COVID-19 in Portugal. First, we fit a SEIR type model without vaccination to the Portuguese data on confirmed cases of COVID-19 by the date of symptom onset, from the beginning of the epidemic until the 23rd January of 2021, to estimate changes in the transmission intensity. Then, by including vaccination in the model we develop different scenarios for the fade-out of the non pharmacological intervention (NPIs) as vaccine coverage increases in the population according to Portuguese vaccination goals. We include a feedback function to mimic the implementation and relaxation of NPIs, according to some disease incidence thresholds defined by the Portuguese health authorities.
Databáze: Directory of Open Access Journals