Increasing Epstein-Barr virus infection in Chinese children: A single institutional based retrospective study. [version 2; peer review: 2 approved, 1 approved with reservations]

Autor: Kiran Devkota, Maio He, Meng Yi Liu, Yan Li, You Wei Zhang
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: F1000Research, Vol 7 (2019)
Druh dokumentu: article
ISSN: 2046-1402
DOI: 10.12688/f1000research.15544.2
Popis: The Epstein-Barr virus (EBV) is a common virus in humans and the most common causative agent of Infectious Mononucleosis. EBV primary infection has recently risen in some countries and children below 2 years of age are highly susceptible. The clinical manifestations in children with EB virus infection involve multiple systems, causing severe illness, meaning attention should be paid during diagnosis and treatment. Objective: This single institution based retrospective study was carried out with the aim of estimating the overall prevalence of EBV infection and identifying high-risk age group among children. Methods: This study include total 253 patients under 15 years of age found to be positive for EBV DNA by serum PCR who were admitted to the Pediatrics Department of Renmin Hospital,(Shiyan, China) during a 4-year period from 2014 to 2017. Patients were divided into three groups; 0-
Databáze: Directory of Open Access Journals