Saliva viral load better correlates with clinical and immunological profiles in children with coronavirus disease 2019
| Autor: | Gilbert T. Chua, Joshua S. C. Wong, Kelvin K. W. To, Ivan C. S. Lam, Felix Y. S. Yau, Wai Hung Chan, Polly P. K. Ho, Jaime S. R. Duque, Cyril C. Y. Yip, Anthony C. K. Ng, Wilfred H. S. Wong, Joyce H. Y. Kwong, Kate F. S. Leung, P. T. Wan, Kelly Lam, Ian C. K. Wong, Janette Kwok, Marco H. K. Ho, Godfrey C. F. Chan, Yu Lung Lau, Patrick Ip, Mike Y. W. Kwan |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Emerging Microbes and Infections, Vol 10, Iss 1, Pp 235-241 (2021) |
| Druh dokumentu: | article |
| ISSN: | 22221751 2222-1751 18219462 |
| DOI: | 10.1080/22221751.2021.1878937 |
| Popis: | Background Pediatric COVID-19 studies exploring the relationships between NPS and saliva viral loads, clinical and immunological profiles are lacking.Methods Demographics, immunological profiles, nasopharyngeal swab (NPS), and saliva samples collected on admission, and hospital length of stay (LOS) were assessed in children below 18 years with COVID-19.Findings 91 patients were included between March and August 20 20. NPS and saliva viral loads were correlated (r = 0.315, p = 0.01). Symptomatic patients had significantly higher NPS and saliva viral loads than asymptomatic patients. Serial NPS and saliva viral load measurements showed that the log10 NPS (r = −0.532, p |
| Databáze: | Directory of Open Access Journals |
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