The liver-to-spleen ratio is a risk factor predicting oxygen demand in COVID-19 patients

Autor: Hiromasa Nakayasu, Shogo Sakurai, Shuichi Sugiyama, Kotaro Shiratori, Kohei Okawa, Yoshihiro Kitahara, Shingo Takahashi, Toshihiro Masuda, Yutaro Kishimoto, Mika Saigusa, Akito Yamamoto, Taisuke Akamatsu, Satoru Morita, Kazuhiro Asada, Toshihiro Shirai
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Infectious Medicine, Vol 2, Iss 2, Pp 105-111 (2023)
Druh dokumentu: article
ISSN: 2772-431X
DOI: 10.1016/j.imj.2023.04.002
Popis: Background: We aimed to investigate risk factors predicting oxygen demand in COVID-19 patients. Methods: Patients admitted to Shizuoka General Hospital with COVID-19 from August 2020 to August 2021 were included. First, we divided patients into groups with and without oxygen demand. Then, we compared patients' clinical characteristics and laboratory and radiological findings to determine factors predicting oxygen demand. Results: One hundred seventy patients with COVID-19 (aged 58±15 years, 57 females) were enrolled. Common comorbidities were cardiovascular diseases (47.6%), diabetes mellitus (28.8%), and dyslipidemia (26.5%). Elder age, higher body mass index, cardiovascular diseases, diabetes mellitus, lower lymphocyte count, albumin, hepatic attenuation value, and the liver-to-spleen ratio (L/S), higher D-dimer, aspartate aminotransferase, lactate dehydrogenase, troponin-T, C-reactive protein, KL-6, chest and abdominal circumference, and visceral fat were found in patients with oxygen demand. According to the multivariate logistic regression analysis, L/S, lymphocyte count, D-dimer, and abdominal circumference under the diaphragm were independent risk factors predicting oxygen demand in COVID-19 patients. Conclusions: On admission, L/S, lymphocyte count, D-dimer, and abdominal circumference were predictive factors for oxygen demand. These factors may help in the appropriate triage of COVID-19 patients in the decision to admit them to the hospital.
Databáze: Directory of Open Access Journals