Association of stressful life events with cognitive impairment in patients with type 2 diabetes mellitus

Autor: Lina Wang, Shanshan Dong, Chenxu Zhao, Zhaoyu Gao, Lei Jiang, Rui Zhang, Tingting Shen, Yingying Guo, Huimin Zhou, Shunjiang Xu
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Journal of Diabetes Investigation, Vol 14, Iss 6, Pp 792-800 (2023)
Druh dokumentu: article
ISSN: 2040-1124
2040-1116
DOI: 10.1111/jdi.14010
Popis: Abstract Aims/Introduction This study was carried out to investigate the relationship of stressful life events (SLEs) with the risk of cognitive impairment in patients with type 2 diabetes mellitus. Materials and Methods A total of 316 patients with type 2 diabetes mellitus aged >45 years were recruited in this study, and data on demographics, medical history, lifestyle characteristics and SLEs were collected. The cognitive status of patients was evaluated with a battery of cognitive function scales. Logistic regression analyses were carried out to evaluate the risk and protective factors for mild cognitive impairment (MCI). Results Participants, including 217 type 2 diabetes mellitus patients with MCI and 99 patients without MCI, were enrolled in the current study. Among the SLEs, the death of an offspring or parent (odds ratio [OR] 1.994, 95% confidence interval [CI] 1.017–3.908) was a risk factor for MCI after adjustment for age and education level. In the subgroup of participants aged
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