| Autor: |
Mark Lee, Haena Lee, John Robert Warren, Pamela Herd |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
SSM: Population Health, Vol 17, Iss , Pp 101037- (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2352-8273 |
| DOI: |
10.1016/j.ssmph.2022.101037 |
| Popis: |
Introduction: Lead exposure negatively affects cognitive functioning among children. However, there is limited evidence about whether exposure to lead in early life impairs later life cognitive functioning. Methods: Participants in the prospective Wisconsin Longitudinal Study cohort (N = 8583) were linked to the 1940 Census, which was taken when they were young children. We estimated the effect of living near a lead mine in childhood on late life memory/attention and language/executive function in 2004 (mean age 64) and 2011 (mean age 71). Results: Lead-exposed children had significantly steeper memory/attention decline between 2004 and 2011 and worse language/executive function at baseline in late life. These long-term effects of lead were not mediated through adolescent IQ or late life SES and health factors. Discussion: Proximity to lead mining in childhood had long-term effects on late life memory/attention decline and language/executive function, reflecting a possible latent influence of lead exposure. More research is needed to understand behavioral and biological pathways underlying this relationship. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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