THE RESULTS OF THE USE OF 5-AMINOSALICYLIC ACID AS AN ANTI-RELAPSE AND MAINTENANCE THERAPY ULCERATIVE COLITIS MODERATE SEVERITY IN CLINICAL PRACTICE

Autor: O. V. Knyazev, A. V. Kagramanova
Jazyk: ruština
Rok vydání: 2018
Předmět:
Zdroj: Медицинский совет, Vol 0, Iss 20, Pp 108-117 (2018)
Druh dokumentu: article
ISSN: 2079-701X
2658-5790
DOI: 10.21518/2079-701X-2017-20-108-117
Popis: Ulcerative colitis (UC) is a chronic disease characterized by immune diffuse inflammation of the mucosa of the colon with mandatory involvement in the inflammatory process of the rectum. The choice of conservative or surgical treatment depends upon the severity of the attack, extent of lesions of the colon, presence of extraintestinal manifestations, duration of disease, efficacy and safety of past therapy and the risk of complications UC. In Russia and abroad for the treatment and prevention of relapses of UC are widely used mesalazine having minimum side effects. Our study shows high adherence of patients to receive drugs 5-ASA and the positive impact of the use of oral medications 5-ASA Salofalk and Asacol for the maintenance of remission in patients UC moderate severity in clinical practice. This study also showed the importance of long-term use (at least 12 months) drugs 5-ASA to maintain remission and reduce the risk of disease recurrence.
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