Predictors for quality of life in older adults: network analysis on cognitive and neuropsychiatric symptoms

Autor: Chaoqun He, Xiangyi Kong, Jinhui Li, Xingyi Wang, Xinqiao Chen, Yuanyi Wang, Qing Zhao, Qian Tao
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: BMC Geriatrics, Vol 23, Iss 1, Pp 1-12 (2023)
Druh dokumentu: article
ISSN: 1471-2318
DOI: 10.1186/s12877-023-04462-4
Popis: Abstract Background Quality of life (QoL) of older adults has become a pivotal concern of the public and health system. Previous studies found that both cognitive decline and neuropsychiatric symptoms (NPS) can affect QoL in older adults. However, it remains unclear how these symptoms are related to each other and impact on QoL. Our aim is to investigate the complex network relationship between cognitive and NPS symptoms in older adults, and to further explore their association with QoL. Methods A cross-sectional study was conducted in a sample of 389 older individuals with complaints of memory decline. The instruments included the Neuropsychiatric Inventory, the Mini Mental State Examination, and the 36-item Short Form Health Survey. Data was analyzed using network analysis and mediation analysis. Results We found that attention and agitation were the variables with the highest centrality in cognitive and NPS symptoms, respectively. In an exploratory mediation analysis, agitation was significantly associated with poor attention (β = -0.214, P
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