Evidence Based Solving Approach in Diagnosis of Primary Hyperparathyroidism with Oral Manifestations: Report of Three Unusual Cases

Autor: Ruchi Bindal, Ajay Kumar, Harkanwal Preet Singh, Sanjiv Kumar Bansal, Aadya Sharma
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: Journal of Laboratory Physicians, Vol 5, Iss 02, Pp 113-117 (2013)
Druh dokumentu: article
ISSN: 0974-2727
0974-7826
DOI: 10.4103/0974-2727.119863
Popis: Primary hyperparathyroidism is a common condition that affects 0.3% of the general population in which excessive production of PTH is there. With changing trends it is diagnosed early and asymptomatically with the improvements in routine biochemical tests and radiological procedures. The late bony complications of the disease have therefore started to decline rapidly. The mandible is the predominantly affected site in the maxillofacial area. Maxillary involvement is rare. Here, we reported series of three cases of 30-40-year-old women with osteolytic lesions and bone resorption in maxilla or mandible. Two of presented cases demonstrated evidence of lesions in both mandible and maxilla which is a very rare event. A thorough diagnostic work-up emphasizing on biochemical and radiographic investigations were discussed. We highlighted the role of endocrinologist, oral and maxillofacial surgeons, general practitioner dentists, and radiologists in diagnosing and managing such patients.
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