Outbreak of occupational Brucella infection caused by live attenuated Brucella vaccine in a biological products company in Chongqing, China, 2020

Autor: Chunbei Zhou, Wenli Huang, Xu Xiang, Jianping Qiu, Dayong Xiao, Ning Yao, Qiang Shu, Shuang Zhou
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Emerging Microbes and Infections, Vol 11, Iss 1, Pp 2544-2552 (2022)
Druh dokumentu: article
ISSN: 22221751
2222-1751
DOI: 10.1080/22221751.2022.2130099
Popis: The northern areas of China are traditional endemic regions for brucellosis in both animals and humans, while occasional outbreaks of brucellosis have been observed in neglected southern provinces. On 16 December 2020, Chongqing Center for Disease Control and Prevention (CQCDC) received a report of 15 Brucella seropositive employees in a biological products company. The CQCDC and the local health administrative department launched an investigation that included identification of cases, laboratory testing of samples, and employees’ interview to identify the cause of this incident. A case-control study was implemented to compare high-risk factors between cases and serology-negative personals. Human and animal serum samples and environmental swabs were collected for testing. A total of 61 recessive infectors were found with an infection rate of 43.57% (61/140). Fisher’s exact test showed that there were significant differences in Brucella infection rates among different post classifications (p = 0.02), working places (p = 0.007), and buildings (p
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