On a Class of Optimal Type Covariate Adjusted Response Adaptive Allocations for Normal Treatment Responses

Autor: Rahul Bhattacharya, Uttam Bandyopadhyay
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Austrian Journal of Statistics, Vol 44, Iss 4 (2015)
Druh dokumentu: article
ISSN: 1026-597X
DOI: 10.17713/ajs.v44i4.69
Popis: In the context of clinical trials for comparing two treatments, a new class of covariate adjusted response adaptive procedures is developed to achieve a balance between clinical optimality and inferential precision. Assuming normally distributed responses, several exact and asymptotic properties are studied and compared with a reasonable alternative under the presence of treatment covariate interaction.
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