Incidence of Viral Agents in Children with CNS Affectation in the State of Zulia, Venezuela, during 2007
| Autor: | John Bermúdez, Alegria Levy, Kelita González, Luz Espina, José Hernández, Leticia Porto, Nereida Valero |
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| Jazyk: | English<br />Spanish; Castilian |
| Rok vydání: | 2011 |
| Předmět: | |
| Zdroj: | Kasmera, Vol 39, Iss 1, Pp 49-58 (2011) |
| Druh dokumentu: | article |
| ISSN: | 0075-5222 2477-9628 |
| Popis: | Introduction: Various viruses affect the central nervous system (CNS) causing encephalitis, mainly in pediatric patients. Objective: To determine the involvement of viral agents for central nervous system (CNS) infections in children in the State of Zulia, Venezuela during the year 2007. Patients and Methods: 109 samples of cerebrospinal fluid (CSF) and serum were collected from patients between 1 day and 14 years of age, who presented clinical symptoms suggestive of CNS involvement and whose conventional CSF bacteriological study proved negative. The CSF Albumin /serum relationship was determined in order to rule out contamination, resulting in 24 optimal pairs for determining the IgM and IgG antibodies specific for herpes simplex virus (HSV), Epstein Barr (EBV), Dengue fever, rubella, measles and Venezuelan Equine Encephalitis (VEE) using the ELISA technique. Results: Of the 24 cases examined, 15 (62.5%) were positive. The causative agents for encephalitis were 11 cases of Dengue (45.8%) (p |
| Databáze: | Directory of Open Access Journals |
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