Comprehensive micro-scaled proteome and phosphoproteome characterization of archived retrospective cancer repositories

Autor: Corinna Friedrich, Simon Schallenberg, Marieluise Kirchner, Matthias Ziehm, Sylvia Niquet, Mohamed Haji, Christin Beier, Jens Neudecker, Frederick Klauschen, Philipp Mertins
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-021-23855-w
Popis: Formalin-fixed, paraffin-embedded (FFPE) specimens are an attractive resource for retrospective clinical proteomics studies. Here, the authors benchmark and optimize proteomics workflows for FFPE sample analysis and provide guidelines on which methods to use for different samples and applications.
Databáze: Directory of Open Access Journals