Quantitative repolarization indices in diagnosis of left ventricular hypertrophy in hypertensive patients
Autor: | T A Sakhnova, E V Blinova, L M Sergakova, D M Ataullakhanova, I E Chazova |
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Jazyk: | ruština |
Rok vydání: | 2009 |
Předmět: | |
Zdroj: | Терапевтический архив, Vol 81, Iss 4, Pp 13-16 (2009) |
Druh dokumentu: | article |
ISSN: | 0040-3660 2309-5342 |
Popis: | Aim. To determine informative value of quantitative parameters of orthogonal ECG repolarization phase in diagnosis of left ventricular hypertrophy (LVH) in hypertensive patients. Material and methods. A total of 210 healthy subjects and 241 hypertensive patients with LVH (LV myocardium mass index > 125 g/m2 in males and > 110 g/m2 in women) comprised two groups - control and test. The study was made of quantitative parameters (components X, Y, Z, modules and angles of azimuth and elevation) of wave T integral vector, wave T maximal vector, ST vector, ventricular gradient; spatial and projection areas of wave T, the angle between integral vectors of spatial waves QRS and T (phi angle). Results. The test group had reduced X, Y components and elevated vectors, their azimuth and phi angle. Most informative for repolarization were components X of T maximal and integral vectors being as informative as Rx+Sz and Cornel product. The method of multiple regression analysis was used to plot discriminant function taking account of most informative indices of depolarization and repolarization - Rx+Sz and X component of T maximal vector. The area under ROC curve for this function was greater than for the variables alone and Cornel product in both groups (0.90 ± 0.02 and 0.86 ± 0.02, p < 0.05 for the control and test group, respectively). Conclusion. Quantitative parameters of repolarization phase can improve LVG diagnosis in hypertensive patients. |
Databáze: | Directory of Open Access Journals |
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