Idiopathic thrombocytopenic purpura

Autor: L Kayal, S Jayachandran, Khushboo Singh
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: Contemporary Clinical Dentistry, Vol 5, Iss 3, Pp 410-414 (2014)
Druh dokumentu: article
ISSN: 0976-237X
0976-2361
DOI: 10.4103/0976-237X.137976
Popis: Idiopathic thrombocytopenic purpura (ITP) is defined as a hematologic disorder, characterized by isolated thrombocytopenia without a clinically apparent cause. The major causes of accelerated platelet consumption include immune thrombocytopenia, decreased bone marrow production, and increased splenic sequestration. The clinical presentation may be acute with severe bleeding, or insidious with slow development with mild or no symptoms. The initial laboratory tests useful at the first visit to predict future diagnosis were erythrocyte count, leukocyte count, anti-glycoprotein IIb/IIIa antibodies, reticulated platelets, plasma thrombopoietin level. Treatment should be restricted to those patients with moderate or severe thrombocytopenia who are bleeding or at risk of bleeding. We present a case report on ITP with clinical presentation, diagnosis and management.
Databáze: Directory of Open Access Journals