Single-center, retrospective study on changes in pain-relieving therapy after bone metastasis detection by bone scintigraphy in prostate cancer patients

Autor: Thamyrys Bessa Silva, Marcella Araugio Soares Cardoso, Jayda Eiras Ramim, Anke Bergmann, Priscilla Brunelli Pujatti
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Brazilian Journal of Pharmaceutical Sciences, Vol 58 (2022)
Druh dokumentu: article
ISSN: 2175-9790
DOI: 10.1590/s2175-97902022e191058
Popis: Abstract Whole-body bone scintigraphy (WB-BS) is used for detecting and monitoring metastatic spread of prostate cancer (PCa) and to investigate bone pain episodes. To investigate the impact of a positive WB-BS on pain-relieving medicine prescription in PCa patients, a single-center, retrospective cohort study with PCa patients classified as positive for bone metastases (BM) by WB-BS was conducted. Demographic, clinical, and ambulatory pain-relieving medicine prescription data were evaluated. Pain-relieving medicines were categorized according to the WHO ‘Analgesic Ladder’. Regimens adopted before and after WB-BS were compared. Differences were considered significant at p
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