Arteriohepatic Dysplasia (Alagille Syndrome) in a Child (Clinical Case)
| Autor: | Ye.V. Omelchenko, A.S. Senatorova, A.F. Shipko, A.V. Omelchenko-Seliukova, M.N. Yermolaiev, M.M. Yermolaieva, Yu.A. Levchenko |
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| Jazyk: | English<br />Ukrainian |
| Rok vydání: | 2015 |
| Předmět: | |
| Zdroj: | Zdorovʹe Rebenka, Vol 10, Iss 2.1.62.1, Pp 128-132 (2015) |
| Druh dokumentu: | article |
| ISSN: | 2224-0551 2307-1168 |
| DOI: | 10.22141/2224-0551.2.1.62.1.2015.83453 |
| Popis: | The article presents a clinical case of a child with a rare nosology — Alagille syndrome. Among the causes of neonatal cholestasis, Alagille syndrome is ranked second, it occurs with an incidence of 1 per 70,000 of newborns. This syndrome is characterized by an insufficient number or by a small diameter of intrahepatic bile ducts, which carry bile from the liver. Alagille syndrome includes a combination of at least three of the five main symptoms: chronic cholestasis, cardiovascular defects, abnormalities of the spine, eye defects, typical craniofacial signs. The only definitive therapy with the formation of liver cirrhosis and without gross defects is liver transplantation. |
| Databáze: | Directory of Open Access Journals |
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