Two-megahertz impedance index prediction equation for appendicular lean mass in Korean older people

Autor: Hyeoijin Kim, Keon-Hyoung Song, Jatin P. Ambegaonkar, Sochung Chung, Kwonchan Jeon, Fang Lin Jiang, Jin Jong Eom, Chul-Hyun Kim
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: BMC Geriatrics, Vol 22, Iss 1, Pp 1-11 (2022)
Druh dokumentu: article
ISSN: 1471-2318
DOI: 10.1186/s12877-022-02997-6
Popis: Abstract Background Whole-body bioelectrical impedance analysis (BIA) has been accepted as an indirect method to estimate appendicular lean mass (ALM) comparable to dual-energy X-ray absorptiometry (DXA). However, single or limited frequencies currently used for these estimates may over or under-estimate ALM. Accordingly, there is a need to measure the impedance parameter with appendicular lean-specific across multiple frequencies to more accurately estimate ALM. We aimed to validate muscle-specific frequency BIA equation for ALM using multifrequency BIA (MF-BIA) with DXA as the reference. Methods 195 community-dwelling Korean older people (94 men and 101 women) aged 70 ~ 92y participated in this study. ALM was measured by DXA and bioimpedance measures at frequencies of 5 kHz ~ 3 MHz were assessed for independent predictive variables. Regression analyses were used to find limb-specific frequencies of bioimpedance, to develop the ALM equations and to conduct the internal cross-validation. The six published equations and the final equation of MF-BIA were externally cross-validated. Results 195 participants completed the measurements of MF-BIA and DXA. Using bivariate regression analysis, the 2 MHz impedance index explained R 2 = 91.5% of variability (P
Databáze: Directory of Open Access Journals