Complexes of Glucarolactones with Water-Soluble Copolymers of N-Vinylpyrrolidone with N-Vinylamine as Inhibitors of β-Glucuronidase Efficacy

Autor: Valerii D. Krasikov, Yulia G. Santuryan, Irina I. Malahova, Alexey G. Ivanov, Nikolay I. Gorshkov, Evgenii F. Panarin
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Polymers, Vol 14, Iss 1, p 105 (2021)
Druh dokumentu: article
ISSN: 2073-4360
DOI: 10.3390/polym14010105
Popis: Water-soluble complexes of N-vinylpyrrolidone/N-vinylamine copolymers with lactones of D-glucuronic acid were obtained and characterized by chromatographic, spectral, and hydrodynamic methods. The complexes efficiently inhibited the enzyme β-glucuronidase that causes the appearance of bladder tumors. The products demonstrated prolonged action and were stable during storage.
Databáze: Directory of Open Access Journals
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