Adaptation of the master antioxidant response connects metabolism, lifespan and feather development pathways in birds

Autor: Gianni M. Castiglione, Zhenhua Xu, Lingli Zhou, Elia J. Duh
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-020-16129-4
Popis: Fast metabolisms tend to shorten lifespans by increasing oxidative damage. This study identifies a gene mutation that keeps a key antioxidant response active, possibly allowing Neoaves bird species to avoid the tradeoff between rapid metabolism and longevity that challenges most mammals, including humans.
Databáze: Directory of Open Access Journals