Distribution of macular pigments in macular telangiectasia type 2 and correlation with optical coherence tomography characteristics and visual acuity

Autor: Ramyaa Srinivasan, Michel M. Teussink, Kenneth R. Sloan, Rekha Priya Kalluri Bharat, Raja Narayanan, Rajiv Raman
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: BMC Ophthalmology, Vol 22, Iss 1, Pp 1-10 (2022)
Druh dokumentu: article
ISSN: 1471-2415
DOI: 10.1186/s12886-022-02483-y
Popis: Abstract Background To estimate macular pigment values in macular telangiectasia (MacTel) Type 2 in comparison with healthy subjects in the South Indian population across different spatial profiles and to quantify the regional differences of macular pigment optical density (MPOD) in MacTel Type 2. Methods In this prospective cross-sectional study, healthy controls and patients diagnosed with various stages of MacTel Type 2 underwent MPOD measurement using dual-wavelength autofluorescence technique with Spectralis HRA + OCT. Results Sixty eyes of 31 healthy subjects and 41 eyes of 22 MacTel type 2 patients were included. We found an overall decrease in MPOD values in MacTel type 2 patients (-0.109, -0.11, -0.001) in comparison with healthy subjects (0.38, 0.23, 0.06) at 1°, 2° & 6° foveal eccentricities (P
Databáze: Directory of Open Access Journals