Human papillomavirus infection in women undergoing in-vitro fertilization: effects on embryo development kinetics and live birth rate

Autor:	Federica Zullo, Valentina Fiano, Anna Gillio-Tos, Sara Leoncini, Ginevra Nesi, Luigia Macrì, Mario Preti, Alessandro Rolfo, Chiara Benedetto, Alberto Revelli, Laura De Marco
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	Human papilloma virus Endometriosis IVF outcome Embryonic development Time-lapse Live birth rate Gynecology and obstetrics RG1-991 Reproduction QH471-489
Zdroj:	Reproductive Biology and Endocrinology, Vol 21, Iss 1, Pp 1-8 (2023)
Druh dokumentu:	article
ISSN:	1477-7827
DOI:	10.1186/s12958-023-01091-9
Popis:	Abstract Backgroud Several studies showed that human papillomavirus (HPV) affects male fertility, but its impact on female fertility and in vitro fertilization (IVF) outcome is not yet clear. Methods Objective of this observational, prospective, cohort study was to evaluate the prevalence of HPV infection in women candidate to IVF, and the effects of HPV infection on the kinetic of embryonic development and on IVF outcome. A total number of 457 women candidate to IVF were submitted to HR-HPV test; among them, 326 underwent their first IVF cycle and were included in the analysis on IVF results. Results 8.9% of women candidate to IVF were HPV-positive, HPV16 being the most prevalent genotype. Among the infertility causes, endometriosis was significantly more frequent in HPV-positive than in negative women (31.6% vs. 10.1%; p
Databáze:	Directory of Open Access Journals
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