RATIONAL APPROACH TO A COMBINATION THERAPY OF FOCAL EPILEPSY
Autor: | I. G. Rudakova |
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Jazyk: | ruština |
Rok vydání: | 2016 |
Předmět: | |
Zdroj: | Эпилепсия и пароксизмальные состояния, Vol 6, Iss 4, Pp 62-66 (2016) |
Druh dokumentu: | article |
ISSN: | 2077-8333 2311-4088 |
Popis: | Abstract: the article presents a discussion of the problem of rational polytherapy (RPT). RPT has become one of the main strategies of modern epilepsy treatment. Early using of the RPT is a tactic of choice for patients with high risk for pharmacoresistant epilepsy (EDF) and for patients with risk of problems that can occur while switching to alternative monotherapy. For early RPT a seizure control can be achieved more quick. That reduces the risks associated with seizures for patients with severe epilepsy. AEDs choice for the RPT should be based on the prevention of the pharmacodynamic and pharmacokinetic side effects. But efficacy data of AEDs in clinical practice should be taking into account. |
Databáze: | Directory of Open Access Journals |
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