Percutaneous nephrolithotomy: Effect of unilateral procedure on contralateral kidney function

Autor: Mehrdad Mohammadi Sichani, Amir Behnamfar, Mohammad Hatef Khorami, Kia Nourimahdavi, Farshid Alizadeh, Mohammad Hossein Izadpanahi
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: Advanced Biomedical Research, Vol 3, Iss 1, Pp 227-227 (2014)
Druh dokumentu: article
ISSN: 2277-9175
DOI: 10.4103/2277-9175.145710
Popis: Background: Although long-term effects of percutaneous nephrolithotomy (PCNL) on renal function and structure have been evaluated, knowledge regarding the immediate effects of surgery on renal function is limited. We conducted this study to evaluate the impact of unilateral PCNL on bilateral renal function during immediate post-operative period. Materials and Methods: From April to September 2012, 40 eligible patients were enrolled in this study and underwent unilateral PCNL. During the post-operative period, creatinine clearances (CrCl) of treated and untreated sides were estimated separately and pattern of changes in bilateral renal function following this procedure was evaluated. Results: Following the operation, CrCl of both kidneys showed a similar pattern of changes, of course more dramatic on treated side. We observed progressive decline in CrCl of both sides followed by bilateral improvement in renal function toward pre-operative values. Conclusions: During the early post-operative period following unilateral PCNL, both kidneys experienced a temporary drop in function warranting more intensive post-operative care.
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