Autor: |
Simon Milette, Masakazu Hashimoto, Stephanie Perrino, Shu Qi, Michely Chen, Boram Ham, Ni Wang, Roman Istomine, Andrew M. Lowy, Ciriaco A. Piccirillo, Pnina Brodt |
Jazyk: |
angličtina |
Rok vydání: |
2019 |
Předmět: |
|
Zdroj: |
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019) |
Druh dokumentu: |
article |
ISSN: |
2041-1723 |
DOI: |
10.1038/s41467-019-13571-x |
Popis: |
It is known that estrogens can affect the immune response to cancer. Here, the authors show that estrogen depletion through ovariectomy reduces the extent of liver metastasis and that this is accompanied by a decrease in the number and function of immunosuppressive cells in the metastatic microenvironment. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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