Electro-Deformation of Fused Cells in a Microfluidic Array Device

Autor: Yan Liu, Xiaoling Zhang, Mengdi Chen, Danfen Yin, Zhong Yang, Xi Chen, Zhenyu Wang, Jie Xu, Yuanyi Li, Jun Qiu, Ning Hu, Jun Yang
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Micromachines, Vol 7, Iss 11, p 204 (2016)
Druh dokumentu: article
ISSN: 2072-666X
DOI: 10.3390/mi7110204
Popis: We present a new method of analyzing the deformability of fused cells in a microfluidic array device. Electrical stresses—generated by applying voltages (4–20 V) across discrete co-planar microelectrodes along the side walls of a microfluidic channel—have been used to electro-deform fused and unfused stem cells. Under an electro-deformation force induced by applying an alternating current (AC) signal, we observed significant electro-deformation phenomena. The experimental results show that the fused stem cells were stiffer than the unfused stem cells at a relatively low voltage (
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