THE EFFICACY OF LONG-TERM WARFARIN THERAPY: THE IMPACT ON THE INCIDENCE OF ISCHEMIC CEREBROVASCULAR DISORDERS AND CLINICAL PREDICTORS OF DEVELOPING SUCH DISORDERS. (Results of a prospective 10-year follow-up study)
| Autor: | E. S. KROPACHEVA, O. A. ZEMLYANSKAYA, A. B. DOBROVOLSKY, E. P. PANCHENKO |
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| Jazyk: | ruština |
| Rok vydání: | 2017 |
| Předmět: | |
| Zdroj: | Атеротромбоз, Vol 0, Iss 2, Pp 115-130 (2017) |
| Druh dokumentu: | article |
| ISSN: | 2307-1109 2658-5952 |
| DOI: | 10.21518/2307-1109-2017-2-115-130 |
| Popis: | Atrial fibrillation (AF) is the most common indication for the long-term oral anticoagulation therapy. For several decades, vitamin K antagonists have been the mainstay of routine clinical practice.A prospective 10-year follow-up of patients with atrial fibrillation receiving warfarin therapy showed that the incidence of all cerebral circulation disorders was 2.59 per 100 patient-years. The warfarin therapy contributed to the prevailing of non-fatal events among the cerebral circulation disorders which occurred during the therapy. The incidence of fatal ischemic strokes was 0.91 per 100 patient-years over the 10-year follow-up study.If the duration of a patient within the target therapeutic range (TTR) was |
| Databáze: | Directory of Open Access Journals |
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