Salicylate Poisoning Potential of Topical Pain Relief Agents: From Age Old Remedies to Engineered Smart Patches

Autor: Ashleigh Anderson, Aaron McConville, Laura Fanthorpe, James Davis
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Medicines, Vol 4, Iss 3, p 48 (2017)
Druh dokumentu: article
ISSN: 2305-6320
DOI: 10.3390/medicines4030048
Popis: The pain relief capabilities of methyl salicylate are well established and a multitude of over-the-counter products populate pharmacy shelves. Over-application of the topical preparation containing the drug, or its accidental ingestion, invariably result in salicylate poisoning and in severe cases can be fatal. The drug has been a regular feature of the US National Poison Database Survey over the past decade and continues to pose a risk to children and adults alike. The aim of the review has been to cast a spotlight on the drug and assess why its use remains problematic, how technology could offer more efficacious delivery regimes, and minimise the possibility of accidental or intentional misuse.
Databáze: Directory of Open Access Journals