Cutaneous approach in toxic epidermal necrolysis
| Autor: | Francisco Carlos Santos Neto, Pedro Salomão Piccinini, Jean Miguel Andary, Lucas Dal Pozzo Sartori, Lucas Tomkowski Cancian, Carlos Oscar Uebel, Milton Paulo de Oliveira |
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| Jazyk: | English<br />Portuguese |
| Rok vydání: | 2017 |
| Předmět: | |
| Zdroj: | Revista Brasileira de Cirurgia Plástica, Vol 32, Iss 01, Pp 128-134 (2017) |
| Druh dokumentu: | article |
| ISSN: | 1983-5175 2177-1235 |
| DOI: | 10.5935/2177-1235.2017RBCP0018 |
| Popis: | INTRODUCTION: Toxic epidermal necrolysis is a severe acute mucocutaneous condition usually induced by drugs associated with a high rate of morbidity and mortality. The care of the mucous lesions and skin and a multidisciplinary approach are very important for the prognosis and future sequelae. OBJECTIVES: To discuss the main aspects of this syndrome through a literature review illustrated by a clinical case. Methods: Review of the literature using the PubMed and SciELO online databases was performed. Articles in English, Portuguese, French, and Spanish were included and illustrated with a pediatric clinical case. The keywords used were as follows: "toxic epidermal necrolysis," "Stevens-Johnson overlap," "necrólise epidérmica tóxica," and "síndrome Stevens-Johnson." RESULTS: We presented data to guide the management of patients with toxic epidermal necrolysis for plastic surgeons, pediatricians, intensivists, dermatologists, and emergency physicians. The case treated had a favorable disease course without sequelae. CONCLUSION: A high level of suspicion is necessary for an adequate diagnosis and risk stratification, and early support measures and treatment should be performed by a multidisciplinary team trained to minimize damage and mortality. |
| Databáze: | Directory of Open Access Journals |
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