An efficient synthesis of β-amino ketone compounds through one-pot three-component Mannich-type reactions using bismuth nitrate as catalyst

Autor: S. Sheik Mansoor, K. Aswin, K. Logaiya, S.P.N. Sudhan
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Journal of Saudi Chemical Society, Vol 19, Iss 4, Pp 379-386 (2015)
Druh dokumentu: article
ISSN: 1319-6103
DOI: 10.1016/j.jscs.2012.04.008
Popis: Three components one-pot Mannich reaction of aromatic ketone, aromatic aldehyde and aromatic amines has been efficiently catalyzed by recyclable bismuth nitrate (Bi(NO3)3, BN) at ambient temperature to give various β-amino carbonyl compounds in high yields. This method has advantages of mild condition, no environmental pollution, and simple work-up procedures. Most importantly, β-amino carbonyl compounds with ortho-substituted aromatic amines are obtained in acceptable to moderate yields by this methodology.
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