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Abstract Introduction Vaccination is a critical public health intervention that significantly reduces morbidity and mortality among children. Despite its importance, vaccination coverage remains suboptimal in many regions, including East Gojam, Amhara Region, Ethiopia. This study investigated the sociodemographic, economic, and cultural determinants of vaccination status among pediatric populations in East Gojam. Methods Using a cross-sectional design, data were collected from 1,900 respondents, categorizing vaccination status as not vaccinated, partially vaccinated, or fully vaccinated. Multinomial logistic regression was used to analyze the impact of predictors such as child age, gender, parental education level, household income, geographic location, access to healthcare, trust in healthcare providers, sources of vaccination information, cultural beliefs, and perceived government support for vaccination. Results The results revealed that higher parental education levels and urban residence positively influence vaccination status. Older children were less likely to be fully vaccinated, indicating a need for targeted outreach. Access to healthcare services and trust in healthcare providers significantly promoted vaccination, whereas negative cultural beliefs and misinformation adversely affected vaccination status. Perceived government support for vaccination was also a significant predictor. Conclusion This study concludes that addressing these multifaceted determinants through educational programs, improved healthcare access, trust-building initiatives, accurate information dissemination, stronger governmental support, targeted outreach for older children, community engagement, and multisectoral collaboration can enhance vaccination coverage and improve public health outcomes in East Gojam and similar settings. |
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