Ferroptosis as a Biological Phase Transition I: avascular and vascular tumor growth

Autor:	Nieto-Villar, J. M., Mansilla, R.
Rok vydání:	2021
Předmět:	Physics - Biological Physics Nonlinear Sciences - Chaotic Dynamics Quantitative Biology - Biomolecules Quantitative Biology - Quantitative Methods
Druh dokumentu:	Working Paper
Popis:	Herewith we discuss a network model of the ferroptosis avascular and vascular tumor growth based on our previous proposed framework. Chiefly, ferroptosis should be viewed as a first order phase transition characterized by a supercritical Andronov Hopf bifurcation, with the emergence of limit cycle. The increase of the population of the oxidized PUFA fragments, take as the control parameter, involves an inverse Feigenbaum, (a cascade of saddle foci Shilnikov's bifurcations) scenario, which results in the stabilization of the dynamics and in a decrease of complexity. Comment: 13 pages, 3 figures
Databáze:	arXiv
Externí odkaz:	http://arxiv.org/abs/2109.02476 Zobrazit plný text záznamu View this record from Arxiv