Optical focusing inside scattering media with time-reversed ultrasound microbubble encoded (TRUME) light
| Autor: | Ruan, Haowen, Jang, Mooseok, Yang, Changhuei |
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| Rok vydání: | 2015 |
| Předmět: | |
| Druh dokumentu: | Working Paper |
| DOI: | 10.1038/ncomms9968 |
| Popis: | Focusing light inside scattering media in a freely addressable fashion is challenging, as the wavefront of the scattered light is highly disordered. Recently developed ultrasound-guided wavefront shaping methods are addressing this challenge, albeit with relatively low modulation efficiency and resolution limitations. In this paper, we present a new technique, time-reversed ultrasound microbubble encoded (TRUME) optical focusing, which is able to focus light with improved efficiency and sub-ultrasound wavelength resolution. This method ultrasonically destructs microbubbles, and measures the wavefront change to compute and render a suitable time-reversed wavefront solution for focusing. We demonstrate that the TRUME technique can create an optical focus at the site of bubble destruction with a size of ~2 microns. Due to the nonlinear pressure-to-destruction response, the TRUME technique can break the addressable focus resolution barrier imposed by the ultrasound focus. We experimentally demonstrate a 2-fold addressable focus resolution improvement in a microbubble aggregate target. Comment: 17 pages, 5 figures |
| Databáze: | arXiv |
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