Gastroprotective and Antioxidant Effects of the Cinnamon, Cumin, Sumac on Indomethacin Induced Gastric Ulcer in Rats
| Autor: | AYDIN BERKTAŞ, Özlem, ODABASOGLU, Fehmi, ATALAY DUMLU, Fadime, KUTLU, Zerrin, ÇADIRCI, Elif, HALICI, Mesut, ÖZTÜRK, Fazlı, ÇAKIR, Ahmet |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Volume: 5, Issue: 2 147-166 Eurasian Journal of Food Science and Technology |
| ISSN: | 2667-4890 |
| Popis: | The gastro-protective effect of water extracts spice of cinnamon, cumin and sumac in indomethacin induced ulcer model in rats was investigated, in vivo and biochemical mechanism of spice extracts were monitored by measuring their antioxidant. For each cumin, cinnamon and sumach extracts 50, 100, 200 and 400 mg/kg, positive control famotidine (FAM) 25 mg/kg and negative control indomethacin (IND) 25 mg/kg dosage form was orally administered. After that catalase (CAT), superoxide dismutase (SOD), myeloperoxidase (MPx) enzyme activities and glutathione (GSH), lipid perxidase (LPO) amounts were measured. In IND induced ulcer group, It is determined that each four dosage form of spices and positive control FAM group significantly decreased the ulcer area (p |
| Databáze: | OpenAIRE |
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