Effect of exercise training on cutaneous microcirculation in rats
| Autor: | Heylen, E., Mansourati, J., Thioub, S., Saïag, B., François Guerrero |
|---|---|
| Přispěvatelé: | Optimisation des régulations physiologiques (ORPHY (EA 4324)), Institut Brestois Santé Agro Matière (IBSAM), Université de Brest (UBO)-Université de Brest (UBO)-Université de Brest (UBO)-Centre Hospitalier Régional Universitaire de Brest (CHRU Brest), Guerrero, François |
| Jazyk: | angličtina |
| Rok vydání: | 2008 |
| Předmět: |
Male
endothelium MESH: Rats [SDV.MHEP.PHY] Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO] Microcirculation education laser doppler flowmetry MESH: Physical Conditioning Animal Rats Inbred WKY MESH: Male Rats MESH: Skin Physical Conditioning Animal MESH: Microcirculation Laser-Doppler Flowmetry [SDV.MHEP.PHY]Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO] Animals rat MESH: Animals exercise training MESH: Laser-Doppler Flowmetry MESH: Rats Inbred WKY Skin |
| Zdroj: | Journal of Sports Medicine and Physical Fitness Journal of Sports Medicine and Physical Fitness, Edizione Minerva Medica, 2008, 48 (2), pp.246-51 Scopus-Elsevier |
| ISSN: | 0022-4707 |
| Popis: | International audience; AIM: Exercise training is known to improve endothelium-dependent relaxation in the coronary and skeletal muscle arteries. However, the effects of exercise training on peripheral nonworking tissue, including microcirculation, are still unclear. Therefore, we investigated the effect of chronic and regular aerobic exercise on cutaneous microvascular endothelial function in rats. METHODS: We assessed the effect of physical training on skin microcirculation in 7 sedentary (SED) and 21 training rats (Wistar-Kyoto), submitted to a treadmill training protocol (15 m/min; 15% incline; 60 min/day; 8 weeks). Training rats were divided into 3 groups, exercising 1 day/week (Ex1), 3 days/week (Ex3) or 5 days/week (Ex5). Cutaneous blood flow was recorded before the beginning of the training protocol, after 4 weeks and at the end of the training program. Hyperemic response (RH) was the flow reaction obtained after sudden release of the garrot. For data analysis, cutaneous vascular conductance (CVC) was indexed as cutaneous blood flow divided by mean arterial blood pressure (in millimeters of mercury, mmHg) and normalized to baseline values. RESULTS: At baseline, CVC was not different among groups (SED or training) at 3 steps of experimental protocol. The hyperemic stimulus significantly increased normalized CVC only in group Ex3 after 4 weeks (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|