[Perfluorocarbons do not induce cytochrome P-448 in the rat liver]

Autor: Vv, Obraztsov, Dg, Shekhtman, Alevtina Grishanova, Vm, Mishin
Předmět:
Zdroj: Europe PubMed Central
Popis: Cytochrome P-450 forms appearing in the liver after injection of methylcholanthrene, polychlorinated biphenyls and perfluorochemical emulsion to rats were studied. Activities of marker enzymes, benzpyrenehydroxylase and 7-ethoxyresorufin-O-deethylase, as well as the interaction of liver microsomal membranes with antibodies against different cytochrome forms were investigated. It was shown that fluorocarbon emulsion containing perfluorodecalin did not induce cytochrome P-448 in the rat liver.
Databáze: OpenAIRE