Treponema species enrich the gut microbiota of traditional rural populations but are absent from urban individuals
| Autor: | Angelakis, E., Bachar, D., Yasir, M., Musso, D., Djossou, F., Gaborit, B., Brah, S., Diallo, A., Ndombe, G.M., Mediannikov, O., Robert, C., Azhar, E.I., Bibi, F., Nsana, N.S., Parra, H.-J., Akiana, J., Sokhna, C., Davoust, B., Dutour, A., Raoult, D. |
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| Přispěvatelé: | Vecteurs - Infections tropicales et méditerranéennes (VITROME), Institut de Recherche Biomédicale des Armées (IRBA)-Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU), King Abdulaziz University, Institut Louis Malardé [Papeete] (ILM), Institut de Recherche pour le Développement (IRD), Centre Hospitalier Andrée Rosemon [Cayenne, Guyane Française], Hôpital de Niamey [Niger], Hôpital Nord [CHU - APHM], Laboratoire national de santé publique, Microbes évolution phylogénie et infections (MEPHI), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Deanship of Scientific Research (DSR), King Abdulaziz University, Jeddah, Saudi Arabia (grant 3-140-1434-HiCi), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut de Recherche Biomédicale des Armées [Brétigny-sur-Orge] (IRBA) |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Médecine humaine et pathologie
bifidobacterium digestive system lcsh:Infectious and parasitic diseases microbiote taxonomie bactérienne [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases traditional living lcsh:RC109-216 [SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology serpulina hyodysenteriae population rurale métagénomique metagenomics [SDV.MHEP.ME]Life Sciences [q-bio]/Human health and pathology/Emerging diseases Geography gut microbiota probiotique [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology microbe stomatognathic diseases probiotics arn ribosomique microflore digestive [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology treponema Original Article Human health and pathology société traditionnelle séquençage de gènes |
| Zdroj: | New Microbes and New Infections New Microbes and New Infections, Wiley Online Library 2019, 27, pp.14-21. ⟨10.1016/j.nmni.2018.10.009⟩ New Microbes and New Infections, Vol 27, Iss, Pp 14-21 (2019) New Microbes and New Infections, 2019, 27, pp.14-21. ⟨10.1016/j.nmni.2018.10.009⟩ New Microbes and New Infections (27), 14-21. (2019) |
| ISSN: | 2052-2975 |
| Popis: | There is a significant gap in our knowledge of the microbe–host relationship between urban and traditional rural populations. We conducted a large-scale study to examine the gut microbiota of different traditional rural and urban lifestyles in human populations. Using high-throughput 16S ribosomal RNA gene amplicon sequencing, we tested urban French, Saudi, Senegalese, Nigerian and Polynesian individuals as well as individuals living in traditional rural societies, including Amazonians from French Guiana, Congolese Pygmies, Saudi Bedouins and Algerian Tuaregs. The gut microbiota from individuals living in traditional rural settings clustered differently and presented significantly higher diversity than those of urban populations (p 0.01). The bacterial taxa identified by class analysis as contributing most significantly to each cluster were Phascolarctobacterium for traditional rural individuals and Bifidobacterium for urban individuals. Spirochaetae were only present in the gut microbiota of individuals from traditional rural societies, and the gut microbiota of all traditional rural populations was enriched with Treponema succinifaciens. Cross-transmission of Treponema from termites or swine to humans or the increased use of antibiotics in nontraditional populations may explain why Treponema is present only in the gut microbiota of traditional rural populations. Keywords: Geography, gut microbiota, metagenomics, probiotics, traditional living, treponema |
| Databáze: | OpenAIRE |
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