High impact of sleeping problems on quality of life in transgender individuals: A cross-sectional multicenter study
| Autor: | Auer, M., Liedl, A., Fuss, J., Nieder, T., Briken, P., Stalla, G., Hildebrandt, T., Biedermann, S., Jung-Sievers, C. |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Adult
Male Sleep Wake Disorders Physiology Economics Emotions Social Sciences Pain lcsh:Medicine Anxiety Biochemistry Severity of Illness Index Transgender Persons Body Mass Index Medizinische Fakultät Mental Health and Psychiatry Medicine and Health Sciences Sex Hormones Body Image Psychology Humans Public and Occupational Health ddc:610 lcsh:Science Mood Disorders Depression lcsh:R Age Factors Biology and Life Sciences Social Support Middle Aged Health Surveys Hormones humanities Cross-Sectional Studies Neurology Chronic Disease Multivariate Analysis Linear Models Quality of Life Female lcsh:Q Physiological Processes Sleep Behavioral and Social Aspects of Health Sleep Disorders Finance Research Article |
| Zdroj: | PLoS ONE, Vol 12, Iss 2, p e0171640 (2017) PLoS ONE PLOS ONE |
| ISSN: | 1932-6203 |
| Popis: | Introduction Studies in the general population suggest that determinants of QoL are often sex-dependent. Sex-dependent analyses of QoL in transgender populations have not been performed so far. Aim To identify sex-specific and potentially modifiable determinants of QoL in transgender patients Methods In this cross-sectional multicentre study including 82 transwomen (TW) and 72 transmen (TM) at different treatment stages, we investigated potential determinants for QoL focusing on the impact of mood (BDI, STAI-X), sleep quality (PSQI), chronic pain (GPQ), body image (FBeK) and social support (SSS). Main outcome measure Health-related quality of life measured with the Short Form (36) Health Survey (SF-36). Results The age-adjusted SF-36 total score and its subscales did not significantly differ between TM and TW. Using a multivariate regression analysis approach, we identified common but also sex-dependent determinants for QoL (Adjusted R2 = 0.228; 0.650 respectively). Accounting for general characteristics such as age, BMI and treatment status, sleep quality according to the PSQI was an independent and strong determinant of QoL in both sexes (β = -0.451, p = 0.003 TM; β = -0.320; p = 0.0029 TW). Chronic pain was a significant independent predictor of QoL in TM (β = -0.298; p = 0.042) but not in TW. In contrast, anxiety (β = -0.451; p< 0.001) being unemployed (β = -0.206; p = 0.020) and insecurity about the own appearance (FBeK) (β = -0.261; p = 0.01) were independent predictors of QoL in TW. The rate of those reporting high sleep disturbances (PSQI ≥5) was high with 79.2% in TW and 81.2% in TM. Accordingly, age-adjusted QoL was also significantly lower in those reporting poor sleep in both sexes. Conclusions Sleep strongly affected QoL in both genders, while other factors, like pain and body image, seem to be gender specific in transgender individuals. |
| Databáze: | OpenAIRE |
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