Pénétration intra-camérulaire de la norfloxacine locale chez l'homme. Etude préliminaire

Autor: Bron, Alain, Pechinot, M., Chirpaz, L., Razakarivony, H., Kamcierkzak, A., Adenis, J. P.
Přispěvatelé: Centre Hospitalier Universitaire de Dijon - Hôpital François Mitterrand (CHU Dijon), Inconnu, ProdInra, Migration
Jazyk: francouzština
Rok vydání: 1990
Předmět:
Zdroj: Bulletin des societes d'ophtalmologie de France
Bulletin des societes d'ophtalmologie de France, 1990, 90 (6-7), pp.631-632, 635-636
Popis: The aim of this bicentric study was to assess the intraocular penetration of topical Norfloxacin. Herein, are only reported the results from one center. Topically applied Norfloxacin 0.3% was given to patients who underwent cataract surgery. The first group received 5 drops between 7.55 A.M. to 8 A.M. and after each hour until cataract surgery. The second one received one drop each quarter from 7 A.M. until the surgery. Aqueous and sera samples were dosed using HPLC. In the first group, the aqueous average was 0.066 mg/l and 0.112 mg/l in the second group. Using a T test and Mann Whitney test, we could not find a significant difference between the two groups.
Databáze: OpenAIRE