Quality of life of hemodialysis patients in Central and Southern Italy: cross-sectional comparison between Hemodiafiltration with endogenous reinfusion (HFR) and Bicarbonate Hemodialysis

Autor: Silvio Borrelli, Roberto Minutolo, Luca De Nicola, Walter De Simone, Emanuele De Simone, Zito, B., Biagio Di Iorio, Lucia Di Micco, Luigi Leone, Antonio Bassi, Angelo Romano, Maria Carla Porcu, Riziero Fini, Edward Vezza, Caterina Saviano, Apice, Ludovica D., Simonelli, R., Vincenzo Bellizzi, Giuseppe Palladino, Olga Credendino, Raffaele Genualdo, Maria Capuano, Pasquale Guastaferro, Filippo Nigro, Vittorio Stranges, Giuseppe Iuianiello, Francesco Saverio Russo, Maria Rita Auricchio, Antonio Treglia, Patrizia Palombo, Nunzio Rifici, Nacca Rg, Caliendo A, Stefania Brancaccio, Giuseppe Conte
Přispěvatelé: Borrelli, Silvio, Minutolo, Roberto, DE NICOLA, Luca, De Simone, Walter, De Simone, Emanuele, Zito, Bruno, Di Iorio, Biagio Raffaele, Di Micco, Lucia, Leone, Luigi, Bassi, Antonio, Romano, Angelo, Porcu, Maria Carla, Fini, Riziero, Vezza, Edward, Saviano, Caterina, D'Apice, Ludovica, Simonelli, Roberto, Bellizzi, Vincenzo, Palladino, Giuseppe, Credendino, Olga, Genualdo, Raffaele, Capuano, Maria, Guastaferro, Pasquale, Nigro, Filippo, Stranges, Vittorio, Iuianiello, Giuseppe, Russo, Francesco Saverio, Auricchio, Maria Rita, Treglia, Antonio, Palombo, Patrizia, Rifici, Nunzio, Nacca, Remo, Caliendo, Alberto, Brancaccio, Stefania, Conte, Giuseppe
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Scopus-Elsevier
The Lens
Popis: in hemodialysis (HD) patients, poor health-related quality of life (HR-QoL) is prevalent and associated with adverse outcomes. HR-QoL is strictly linked to nutritional status of HD patients. Hemodiafiltration with endogenous reinfusion (HFR) is an alternative dialysis technique that combines diffusion, convection and absorption. It reduces burden of inflammation and malnutrition and this effect may cause beneficial effect on HR-QoL. However no data on HR-QoL in HFR is currently available.we designed a cross-sectional multicentre study in order to compare the HR-QoL in patients treated with HFR versus Bicarbonate HD (BHD). We enrolled adult patients HFR treated for at least 6 months, with life expectancy greater than six months and without overt cognitive deficit. The recruited patients in HFR were matched for age, gender, dialytic vintage and performance in activities of daily living (Barthel index) with BHD treated patients. SF-36 questionnaire for the assessment of HR-QoL was administered.one hundred fourteen patients (57 HFR vs 57 BHD) were enrolled (age 65.413.5 years; dialysis vintage 5.4 (3.3-10.3) years; 53% males) from 18 dialysis non-profit centres in central and southern Italy. As result of matching, no difference in age, gender, dialytic age and Barthel index was found between HFR and BHD patients. In HFR patients we observed better values of physical component score (PCS) of SF-36 than BHD patients (P=0.048), whereas no significant difference emerged in the mental component score (P=0.698). In particular HFR patients were associated with higher Physical Functioning (P=0.045) and Role Physical (P=0.027).HFR is associated with better physical component of HR-QoL than BHD, independently of age, gender, dialysis vintage and invalidity score. Whether these findings translate into a survival benefit must be investigated by longitudinal studies.
Databáze: OpenAIRE
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