Effect of haemodialysate and its peptide fractions on acetylcholinesterase activity in erythrocytes from healthy subjects and patients with terminal renal failure

Autor:	O, Smoleński, Z, Tabarowski, H, Miszta, Z, Dabrowski
Rok vydání:	1993
Předmět:	Erythrocytes Renal Dialysis Acetylcholinesterase Humans Kidney Failure Chronic In Vitro Techniques Toxins Biological Uremia
Zdroj:	International urology and nephrology. 25(5)
ISSN:	0301-1623
Popis:	The effects of haemodialysate and its three peptide fractions on acetylcholinesterase (AChE, E.C. 3.1.1.7) activity in erythrocytes from healthy subjects and patients with terminal renal insufficiency treated by repeated haemodialyses have been studied. It was shown that erythrocytes from haemodialysed patients display an increased activity of the enzyme if compared with those from healthy subjects. Neither haemodialysate nor any of its three peptide fractions, when incubated with erythrocytes from healthy subjects and from haemodialysed patients, have altered the activity of the enzyme, except for fraction III at the highest concentration. This fraction exerted an inhibitory effect on AChE activity of the erythrocyte derived from healthy subjects.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::ffacf9b05802256161fadf44793d5cb3 https://pubmed.ncbi.nlm.nih.gov/8270380 Zobrazit plný text záznamu Full text from SpringerLink