Growth and differentiation of Vero cells cultivated in three-dimensional type 1 collagen

Autor:	M L, Wada, B de C, Vidal
Rok vydání:	1991
Předmět:	Tendons Animals Cattle Cell Differentiation Collagen Vero Cells Cell Division
Zdroj:	Cytobios. 67(269)
ISSN:	0011-4529
Popis:	Vero cells grown in a three-dimensional arrangement of type 1 collagen were phenotypically altered. Such alterations consisted of variations in cellular form and reactivity to toluidine blue. After 22 days of incubation the Vero cells formed three-dimensional arrangements in both tubular form and cellular mass. A reduction in the collagenous substrate was observed in the culture and the alteration noted in the birefringence of the extracellular matrix was attributed to enzymatic action. This model demonstrates a good in vitro system for the study of collagenase activation and for in vitro tests with collagen.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::f798d186801dff8dfd16103f8f01df12 https://pubmed.ncbi.nlm.nih.gov/1954782 Zobrazit plný text záznamu