Second trimester levels of maternal serum inhibin A in pregnancies affected by fetal neural tube defects

Autor:	G M, Lambert-Messerlian, G E, Palomaki, J A, Canick
Rok vydání:	2000
Předmět:	Anencephaly Fetal Diseases Estriol Mosaicism Pregnancy Pregnancy Trimester Second Humans Turner Syndrome Female Inhibins Neural Tube Defects Spinal Dysraphism
Zdroj:	Prenatal diagnosis. 20(8)
ISSN:	0197-3851
Popis:	Inhibin A is effective as a second trimester maternal serum marker for Down syndrome screening. In the present study, inhibin A levels were measured in second trimester maternal serum samples from 28 pregnancies affected with open neural tube defects; 12 associated with open spina bifida and 16 associated with anencephaly. Each measurement was expressed as a multiple of the median (MoM) for control singleton pregnancies (n=1464) of the same completed week of gestation. Inhibin A levels were not significantly altered in cases of open neural tube defects; the median value was 0.96 MoM in cases of open spina bifida and 1.19 MoM in cases of anencephaly. Therefore, second trimester maternal serum inhibin A levels will not have an impact on prenatal detection of open neural tube defects.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::f66045ef772c587d869b21be73aa617b https://pubmed.ncbi.nlm.nih.gov/10951483 Zobrazit plný text záznamu Plný text