| Autor: |
Kwanchanok, Uppakara, Sopana, Jamornwan, Liang-Xing, Duan, Kai-Rui, Yue, Chotchanit, Sunrat, Erik W, Dent, Sheng-Biao, Wan, Witchuda, Saengsawang |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
ACS chemical neuroscience. 11(11) |
| ISSN: |
1948-7193 |
| Popis: |
Neurodegenerative diseases are irreversible conditions that result in progressive degeneration and death of nerve cells. Although the underlying mechanisms may vary, oxidative stress is considered to be one of the major causes of neuronal loss. Importantly, there are still no comprehensive treatments to completely cure these diseases. Therefore, protecting neurons from oxidative damage may be the most effective therapeutic strategy. Here we report a neuroprotective effects of a novel hybrid compound (dlx-23), obtained by conjugating α-lipoic acid (ALA), a natural antioxidant agent, and 3 |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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