Predictors of success of high-flow nasal cannula in the treatment of acute hypoxemic respiratory failure

Autor: R, Artacho Ruiz, B, Artacho Jurado, F, Caballero Güeto, A, Cano Yuste, I, Durbán García, F, García Delgado, J A, Guzmán Pérez, M, López Obispo, I, Quero Del Río, F, Rivera Espinar, E, Del Campo Molina
Rok vydání: 2018
Zdroj: Medicina intensiva. 45(2)
ISSN: 2173-5727
Popis: High-flow nasal cannula (HFNC) therapy is used in the treatment of acute respiratory failure (ARF) and is both safe and effective in reversing hypoxemia. In order to minimize mortality and clinical complications associated to this practice, a series of tools must be developed to allow early detection of failure. The present study was carried out to: (i)examine the impact of respiratory rate (RR), peripheral oxygen saturation (SpOA retrospective study was carried out in the medical-surgical ICU of Hospital de Montilla (Córdoba, Spain). Patients diagnosed with hypoxemic ARF and treated with HFNC from January 2016 to January 2018 were included.Out of 27 patients diagnosed with ARF, 19 (70.37%) had hypoxemic ARF. Fifteen of them (78.95%) responded satisfactorily to HFNC, while four (21.05%) failed. After two hours of treatment, RR proved to be the best predictor of success (area under the ROC curve [AUROC] 0.858; 95%CI: 0.63-1.05; P=.035). For this parameter, the optimal cutoff point was 29rpm (sensitivity 75%, specificity 87%). After 8hours of treatment, FiORR after two hours of treatment, and FiO
Databáze: OpenAIRE