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Autor: Zian, Xue, Huiti, Li, Wenhao, Xie, Ying, Xu, Lu, Zhou, Zhi-Bei, Qu
Rok vydání: 2022
Zdroj: ACS medicinal chemistry letters. 13(12)
ISSN: 1948-5875
Popis: Hypoxia-inducible factor, also known as HIF, is a transcriptional factor universally found in mammalian cells. HIF-1 is one of the HIF-families and acts as a heterodimer consisting of α and β subunits. It is found to play significant roles in pathologic conditions such as tumor development and metastasis. Here, we first report benzo[
Databáze: OpenAIRE