| Autor: |
J E, Fahy, S F, Quan, J W, Bloom, M J, Halonen |
| Rok vydání: |
1999 |
| Předmět: |
|
| Zdroj: |
Research communications in molecular pathology and pharmacology. 102(1) |
| ISSN: |
1078-0297 |
| Popis: |
Activation of the Fas receptor (Fas; CD95) on eosinophils induces apoptosis and may play a role in controlling eosinophil number in blood and tissue. To determine whether Fas expression on eosinophils is different between asthmatics and non-asthmatics, eosinophils were isolated from the peripheral blood using a three-step procedure of dextran sedimentation, ficoll hypaque separation and negative selection with anti-CD16 monoclonal antibody bound to magnetic beads. Fas expression was quantified by flow cytometry. Fas expression and the percentage of eosinophils expressing Fas were not different between asthmatics (n=9) and non-asthmatics (n=14). |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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