Systematic review and meta-analysis of venous thromboembolism in otolaryngology-head and neck surgery

Autor:	Sami P, Moubayed, Antoine, Eskander, Moustafa W, Mourad, Sam P, Most
Rok vydání:	2016
Předmět:	Male Incidence Venous Thromboembolism Prognosis Risk Assessment Survival Analysis Disease-Free Survival Otorhinolaryngologic Surgical Procedures Otorhinolaryngologic Diseases Otorhinolaryngologic Neoplasms Postoperative Complications Head and Neck Neoplasms Humans Female Pulmonary Embolism
Zdroj:	Headneck. 39(6)
ISSN:	1097-0347
Popis:	The purpose of this study was to present our systematic review and meta-analysis of the data on venous thromboembolism (VTE; deep venous thrombosis [DVT] and/or pulmonary embolism [PE]) in otolaryngology-head and neck surgery (OHNS).PubMed and Scopus databases were searched for studies reporting VTE in OHNS. Incidence of VTE and bleeding is reported and meta-analyzed overall and for chemoprophylaxis and squamous cell carcinoma (SCC)/free flap subgroups.A total of 23 studies were included with a total of 618,264 patients. Incidence of VTE was 0.4%. The incidence of bleeding complications was 0.9%. The addition of chemoprophylaxis did not result in a decreased VTE incidence (odds ratio [OR], 0.86), but produced an increased risk of bleeding (OR, 3.78). The overall OR for VTE in SCC/free flap cases was 6.28.Chemoprophylaxis may not be necessary in the OHNS non-SCC or free flap patient population and must be balanced against an increased risk of bleeding. © 2017 Wiley Periodicals, Inc. Head Neck 39: 1249-1258, 2017.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::e8b47c93a0eff790a40579d45d13823b https://pubmed.ncbi.nlm.nih.gov/28370756 Zobrazit plný text záznamu Plný text