Occult perineural tumor infiltration of the trigeminal nerve. Diagnostic considerations
| Autor: | M W, ten Hove, J S, Glaser, N J, Schatz |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Aged
80 and over Gadolinium DTPA Male Biopsy Middle Aged Pentetic Acid Carcinoma Adenoid Cystic Magnetic Resonance Imaging Carcinoma Basal Cell Peripheral Nervous System Neoplasms Carcinoma Squamous Cell Organometallic Compounds Humans Cranial Nerve Neoplasms Female Neoplasm Invasiveness Peripheral Nerves Trigeminal Nerve Aged |
| Zdroj: | Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society. 17(3) |
| ISSN: | 1070-8022 |
| Popis: | Cutaneous carcinomas of the face, and some nasopharyngeal carcinomas, may present with facial dysesthesias and/or facial nerve palsies in the absence of visible masses. Even with frank ophthalmoplegia, occult tumors that present in this matter may elude detection, for which reason specific diagnostic studies must be employed. We report seven cases of trigeminal nerve infiltration by occult tumors (five squamous cell carcinomas, one basal cell carcinoma, and one adenoid cystic carcinoma), and outline the clinical course, diagnostic investigations, and the subsequent management of these patients. The importance of establishing an early diagnosis before the tumor has transgressed the basal foramina is emphasized, as tumor infiltration of the cavernous sinus carries a more guarded prognosis. The use of magnetic resonance imaging to identify involved peripheral nerve branches that may then be biopsied is suggested. The patho-physiological mechanisms of neurotropic spread of tumor are reviewed. |
| Databáze: | OpenAIRE |
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