| Autor: |
A, Oruc, A, Ersoy, A A, Kocaeli, A, Yildiz, O O, Gul, E, Ertürk, C, Ersoy |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
International Journal of Organ Transplantation Medicine |
| ISSN: |
2008-6482 |
| Popis: |
Background: Persistent hypercalcemia and hyperparathyroidism after successful kidney transplantation can be detrimental in some recipients and should be ameliorated. Objective: To point out the concerns regarding resistance to cinacalcet in kidney transplant recipients with persistent hypercalcemia. Methods: 14 renal transplant recipients who received cinacalcet treatment because of persistent hypercalcemia were included in the study. Serum creatinine, estimated glomerular filtration rate (eGFR), calcium, phosphorus, and intact parathyroid hormone (PTH) levels at the baseline and throughout the treatment, and ultrasonography and parathyroid scintigraphy findings were recorded. Results: Cinacalcet treatment was initiated after a mean±SD of 20.7±19.7 months of transplantation and maintained for 16.9±7.9 months. Serum calcium levels were significantly decreased with the cinacalcet treatment. There were no significant changes in serum creatinine, eGFR, phosphorus, and PTH levels. In all participants, serum calcium levels were increased from 9.8±0.6 to 11.1±0.6 mg/dL (p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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